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[Effect of lipid peroxidation on DNA synthesis in Ehrlich ascites carcinoma cells]

G A Popov, V V Konev

Biokhimiia (Moscow, Russia)

|July 1, 1984

Abstract:

The effect of lipid peroxidation (LPO) induced by Fe2+ and linoleic acid hydroperoxides in intact cells on the rate of DNA synthesis was investigated. It was found that intensification of LPO is accompanied by a decrease of DNA synthesis rate. Under effects of linoleic acid hydroperoxides, the repression of DNA synthesis is enhanced.

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