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Related Experiment Videos

Blastomycosis during pregnancy.

L Daniel, I E Salit

    Canadian Medical Association Journal
    |October 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Disseminated blastomycosis in a pregnant woman was successfully treated with amphotericin B postpartum. The infant remained healthy, highlighting safe treatment options for invasive fungal infections during pregnancy.

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    Area of Science:

    • Medical Mycology
    • Immunology
    • Obstetrics

    Background:

    • Blastomycosis is an invasive fungal infection caused by *Blastomyces dermatitidis*.
    • Pregnancy can be a state of altered immunity, potentially increasing susceptibility to infections.
    • Disseminated fungal infections during pregnancy pose risks to both mother and fetus.

    Observation:

    • A 31-year-old woman at 36 weeks gestation presented with disseminated blastomycosis affecting lungs, skin, and bones.
    • No antifungal therapy was administered during pregnancy.
    • The patient delivered a healthy, uninfected infant, with a healthy placenta.

    Findings:

    • Postpartum treatment with amphotericin B led to complete resolution of the mother's blastomycosis symptoms.
    • Literature review indicates increased susceptibility to systemic fungal infections during pregnancy due to immunosuppression.

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  • Disseminated blastomycosis in pregnant individuals warrants prompt treatment with amphotericin B.

    • Implications:

    • Amphotericin B appears to be a safe and effective treatment for disseminated blastomycosis in the postpartum period.
    • Early diagnosis and treatment are crucial for managing invasive fungal infections in pregnant women.
    • Further research into the management of systemic mycoses during pregnancy is warranted.