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Serum copper concentration significantly less in abnormal pregnancies.
Clinical Chemistry
|October 1, 1984
Summary
Maternal serum copper levels were lower in abnormal pregnancies compared to normal ones. Copper concentration did not change with gestational age between 15-18 weeks in normal pregnancies.
Area of Science:
- Biochemistry
- Obstetrics
- Maternal-Fetal Medicine
Background:
- Copper is an essential trace element vital for fetal development.
- Altered trace element levels, including copper, have been implicated in pregnancy complications.
Purpose of the Study:
- To investigate maternal serum copper concentrations in normal versus abnormal pregnancies.
- To determine the relationship between gestational age and serum copper levels in normal pregnancies.
Main Methods:
- Serum samples were collected from 244 normal and 15 abnormal pregnancies.
- Copper concentration in maternal serum was quantified using established analytical methods.
Main Results:
- Maternal serum copper levels were significantly lower in the group of abnormal pregnancies.
- No significant variation in copper concentration was observed with advancing gestational age (15-18 weeks) in normal pregnancies.
Conclusions:
- Lower maternal serum copper may be associated with abnormal pregnancy outcomes.
- Gestational age within the second trimester (15-18 weeks) is not a significant factor for serum copper levels in normal pregnancies.