[Oxygen balance and the effect of antihypoxic preparations in fluorine poisoning]

Long-term inhalations of fluoride at concentrations of 0.58 and 2.75 mg/m3 distrub oxygen regimen in experimental animals (O2 consumption, tension and utilization in the muscle, tissue respiration). During fluorine intoxication, some of the antihypoxic agents (NAD X H, adenine nucleotides, guthimin, bemitil, apressin and glutamic acid) exert a beneficial therapeutic effect. Administration of the glycolysis substrates, NAD, NADP, cytochrome c and sodium hydroxybutyrate, did not exert any marked therapeutic action.