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Blood components in an elderly population.

P O Osterlind, I Alafuzoff, A C Löfgren

    Gerontology
    |January 1, 1984
    PubMed
    Summary
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    Reference intervals for 18 blood components were established in the elderly. Key findings include broader value ranges, lower plasma folate and potassium, and higher erythrocyte sedimentation rate, creatinine, and cholesterol in women.

    Area of Science:

    • Gerontology
    • Clinical Biochemistry
    • Hematology

    Background:

    • Establishing accurate reference intervals is crucial for diagnosing and monitoring health conditions in aging populations.
    • Previous reference intervals may not accurately reflect physiological changes associated with advanced age.

    Purpose of the Study:

    • To determine the reference intervals for 18 blood components in individuals in their 8th decade of life.
    • To compare these intervals with those established for younger populations.

    Main Methods:

    • Blood samples were collected from elderly individuals (8th decade).
    • Levels of 18 blood components were measured.
    • Statistical analysis was performed to establish reference intervals.

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    Main Results:

    • Broader reference ranges were observed for most blood components in the elderly.
    • Lower plasma folate and plasma potassium levels were noted compared to younger individuals.
    • Higher erythrocyte sedimentation rate, plasma creatinine, and serum cholesterol (in women) were found in the elderly.

    Conclusions:

    • The study provides age-specific reference intervals for key blood components in the elderly.
    • These findings highlight significant physiological differences in blood parameters between elderly and younger populations.
    • Updated reference intervals are essential for accurate clinical assessment in geriatric patients.