Chondrosarcoma in the radius of a horse

An aged Thoroughbred stallion was examined because of progressive lameness, carpal swelling, and weight loss. Radiography revealed a destructive lesion in the caudomedial, distal portion of the radius. Chondrosarcoma was diagnosed by tumor-core biopsy. Gross and histologic evaluation of the neoplasm after necropsy revealed a locally invasive chondrosarcoma at the distal end of the radius that infiltrated the radiocarpal joint capsule and invaded the carpal bones. The malignant nature of this tumor was evident by its invasiveness and histologic features of cell pleomorphism and presence of mitotic figures.