Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Early surgery for severe aortic regurgitation.

Y Louagie, C Brohet, E Lopez

    The Journal of Cardiovascular Surgery
    |July 1, 1984
    PubMed
    Summary

    Early aortic valve replacement (AVR) for severe aortic regurgitation (AR) is recommended, even in asymptomatic patients, to improve long-term survival. Altered left ventricular function indicates the need for prompt surgical intervention.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effect of anti-gonadotropin-releasing factor vaccine and band castration on indicators of welfare in beef cattle.

    Journal of animal science·2015
    Same author

    Intermediate band solar cell with extreme broadband spectrum quantum efficiency.

    Physical review letters·2015
    Same author

    Downward trends in the prevalence of childhood overweight in two pilot towns taking part in the VIASANO community-based programme in Belgium: data from a national school health monitoring system.

    Pediatric obesity·2015
    Same author

    A pilot study on the feasibility of European harmonized human biomonitoring: Strategies towards a common approach, challenges and opportunities.

    Environmental research·2015
    Same author

    Habitable evaporated cores: transforming mini-Neptunes into super-Earths in the habitable zones of M dwarfs.

    Astrobiology·2015
    Same author

    Experimental and ab initio studies of the reactive processes in gas phase i-C3H7Br and i-C3H7OH collisions with potassium ions.

    The Journal of chemical physics·2014

    Area of Science:

    • Cardiology
    • Cardiac Surgery

    Background:

    • Severe aortic regurgitation (AR) can lead to left ventricular (LV) dysfunction.
    • The optimal timing for aortic valve replacement (AVR) in AR remains a critical clinical question.

    Purpose of the Study:

    • To evaluate the long-term outcomes of AVR in patients with isolated AR.
    • To assess the impact of preoperative functional class on survival after AVR for AR.

    Main Methods:

    • Retrospective analysis of 114 patients undergoing AVR for isolated AR between 1965 and 1981.
    • Preoperative assessment included NYHA functional class, cardiac catheterization, and angiography.
    • Left ventricular volumes and pressures were analyzed in relation to functional class.

    Main Results:

    Related Experiment Videos

    • Operative mortality was 1.7% (2 deaths in NYHA class III).
    • Five-year survival was 82.7%, with significantly better late survival in patients with better preoperative functional class (P < 0.03).
    • Elevated LV end-diastolic and end-systolic volumes, and diminished LV end-systolic pressure to volume ratio were observed even in mildly symptomatic patients.

    Conclusions:

    • Severe AR with impaired LV function is an indication for early AVR, irrespective of symptoms.
    • Timely surgical intervention can improve long-term survival in patients with AR.
    • Preoperative functional status is a significant predictor of long-term survival after AVR for AR.