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Updated: Aug 8, 2026
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Isolation of Normal and Cancer-associated Fibroblasts from Fresh Tissues by Fluorescence Activated Cell Sorting (FACS)
Published on: January 14, 2013
Solitary fibrofolliculoma
Journal of the American Academy of Dermatology
|August 1, 1984
Summary
This case report details the first instance of a solitary fibrofolliculoma, a skin condition typically found in multiples. Histopathology reveals characteristic follicular and stromal changes, offering new insights into this rare entity.
Area of Science:
- Dermatopathology
- Histopathology
- Oncology
Background:
- Fibrofolliculoma is a rare benign skin neoplasm.
- It is typically characterized by multiple lesions.
- Previous literature has not documented solitary presentations.
Observation:
- A unique case of a solitary fibrofolliculoma is presented.
- Histopathologic examination revealed a central hair follicle.
- This was surrounded by a dense fibromucinous stroma with epithelial bands.
Findings:
- The histopathologic findings are characteristic of fibrofolliculoma.
- The solitary nature of this presentation is unprecedented.
- This challenges the established understanding of fibrofolliculoma occurrence.
Implications:
- This case expands the clinical spectrum of fibrofolliculoma.
- It highlights the importance of considering solitary lesions in differential diagnoses.
- Further research may elucidate the pathogenesis of solitary versus multiple fibrofolliculomas.
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