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Panic attack syndrome.

J T Van Winter, G B Stickler

The Journal of Pediatrics

|October 1, 1984

Summary

This summary is machine-generated.

Panic attack syndrome, a biochemical illness, shows an autosomal dominant inheritance pattern across four generations. Pediatric cases were also identified, suggesting an endogenous origin for this disorder.

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Area of Science:

Genetics
Psychiatry
Biochemistry

Background:

Panic attack syndrome has been recognized for over a century under various names.
Previous research has not detailed the diagnosis of panic attack syndrome in pediatric patients.

Observation:

The study reports on panic attack syndrome observed in four generations of a single family.
Six additional pediatric patients diagnosed with panic attack syndrome were also included in the study.

Findings:

The panic attack syndrome demonstrates a clear autosomal dominant mode of inheritance.
Evidence suggests an endogenous, biochemical basis for the syndrome.
Sodium lactate infusion triggers panic attacks, while monoamine oxidase inhibitors and beta-blocking agents alleviate symptoms.

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Implications:

This research provides the first report of panic attack syndrome diagnosis in children.
Findings support the classification of panic attack syndrome as a biochemical illness.
Pharmacological treatments including imipramine hydrochloride, propranolol hydrochloride, phenelzine sulfate, and alprazolam are effective, with some also addressing comorbid depression.