Related Experiment Video
Updated: Jul 15, 2026
09:50
Procedure for Human Saphenous Veins Ex Vivo Perfusion and External Reinforcement
Published on: October 1, 2014
Homologous veins as an arterial substitute: long-term results
Journal of Vascular Surgery
|March 1, 1984
Summary
Homologous vein grafts show variable patency, with 50% occlusion by 1 year but sustained function in 60% for over 5 years. Despite requiring revisions, they are a viable option when autogenous tissue is unavailable.
Area of Science:
- Vascular Surgery
- Biomaterials Science
- Immunology
Background:
- Homologous vein grafts have been utilized in various vascular reconstructions.
- Previous operations were common in patients receiving these grafts, often for limb salvage.
Purpose of the Study:
- To evaluate the long-term patency and outcomes of homologous vein grafts in diverse arterial positions.
- To assess the suitability of homologous saphenous veins as substitutes for autogenous tissue.
Main Methods:
- Retrospective analysis of 129 homologous vein grafts implanted between 1968 and 1982.
- Life-table method used to calculate cumulative patency rates.
- Grafts analyzed in femoropopliteal, aortocoronary, and aortopulmonary positions, among others.
Main Results:
- Lower extremity graft patency ranged from 0 to 121 months (mean 22.4 months).
- 50% of grafts occluded by 1 year; however, 60% of remaining grafts remained functional for over 5 years.
- Aortocoronary bypass grafts had 50% occlusion at 1 year. Eight of 13 pulmonary artery shunts remained patent.
Conclusions:
- Homologous vein grafts require frequent revisions and thrombectomies to maintain patency.
- Graft outcome is unpredictable, largely due to graft antigenicity.
- Homologous saphenous veins can be a suitable substitute when autogenous tissue is unavailable, provided significant effort is invested in maintaining patency.
Related Concept Videos
01:17Veins
Veins are an integral part of our circulatory system, serving as the blood vessels that transport blood from all body regions to the heart. They are a network of hollow tubes that carry blood low in oxygen from the body's cells back to the heart for reoxygenation. Veins are crucial for maintaining the body's overall fluid balance and the continuous circulation of blood.
Structure of Veins:
The structure of veins is specifically designed to assist in the low-pressure transportation of blood...
Structure of Veins:
The structure of veins is specifically designed to assist in the low-pressure transportation of blood...
01:19Anastomoses
In human anatomy, anastomosis refers to a connection or opening between two things, particularly between blood vessels or other tubular structures. The term is derived from the Greek term 'anastomosis,' which means 'outlet' or 'opening.' This natural network of connections plays a critical role in the survival and functionality of the human body.
Anastomoses can be formed at arterial, venous, and lymphatic vessels.
Arterial Anastomosis: These occur between arteries. They are most common in...
Anastomoses can be formed at arterial, venous, and lymphatic vessels.
Arterial Anastomosis: These occur between arteries. They are most common in...
01:11Overview of Systemic Veins
Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
01:19Veins of Thorax
The azygos system is a crucial part of the body's circulatory system and drains most of the thorax. It comprises the azygos, hemiazygos, and accessory hemiazygos veins.
The azygos vein, positioned just right of the midline and anterior to the vertebral column, begins at the junction of the right ascending lumbar and subcostal veins, terminating in the superior vena cava. This vein drains blood from the right side of the thoracic wall, thoracic viscera, and posterior abdominal wall.
The...
The azygos vein, positioned just right of the midline and anterior to the vertebral column, begins at the junction of the right ascending lumbar and subcostal veins, terminating in the superior vena cava. This vein drains blood from the right side of the thoracic wall, thoracic viscera, and posterior abdominal wall.
The...
01:17Veins of Upper Limbs
The human circulatory system, a marvel of biological engineering, is a complex network of vessels that transport blood throughout the body. Among these, the veins responsible for carrying blood from the upper limbs are divided into two categories: deep and superficial.
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
01:15Veins of Lower Limbs
The human body consists of an intricate network of veins responsible for the crucial task of blood drainage from the lower limbs. These veins can be categorized into two main types: deep veins and superficial veins.
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the knee,...
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the knee,...