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Results of treatment of center hemodialysis patients
Insights
Hemodialysis patients faced risks of myocardial infarction and stroke, which contributed to nearly half of the deaths. However, many patients maintained employment and activity, with 5-year survival rates of 52% for dialysis alone and 65% with transplantation.
Area of Science:
- Nephrology
- Cardiovascular Medicine
- Public Health
Background:
- Maintenance hemodialysis was initiated for 483 patients between 1963 and 1977.
- Pre-dialysis cardiovascular events were infrequent (18 myocardial infarctions, 6 strokes).
Purpose of the Study:
- To evaluate the outcomes of patients undergoing maintenance hemodialysis.
- To assess the incidence of cardiovascular complications and survival rates.
Main Methods:
- Retrospective analysis of 483 patients on maintenance hemodialysis.
- Tracking of myocardial infarction, stroke, employment, activity levels, and survival.
Main Results:
- 30 patients had acute myocardial infarction and 45 had a stroke post-dialysis.
- These cardiovascular events caused 48 of 98 deaths during maintenance dialysis.
- 5-year survival was 52% for dialysis alone and 65% including first allografts.
Conclusions:
- Hemodialysis patients are at significant risk for cardiovascular events and mortality.
- Despite risks, a substantial portion of patients maintain employment and activity.
- Renal transplantation improves overall survival rates in hemodialysis patients.
Abstract:
Four hundred eighty-three patients were maintained by hemodialysis in an outpatient hemodialysis center at the Mayo Clinic between 1963 and 1977. Although only 18 patients had experienced a myocardial infarction and 6 had had a cerebral infarction before beginning dialysis, 30 subsequently had acute myocardial infarction and 45 had a stroke. These two complications accounted for 48 of the 98 deaths that occurred during maintenance dialysis. Despite such complications, 183 patients were employed, 124 remained active at home or at school, and 115 were totally disabled. Survival of patients maintained solely by dialysis was 52% at 5 years. For the group as a whole, including patients who received their first allograft, the survival rate at 5 years was 65%.
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