[Chronic paroxysmal hemicrania. A review based on personal cases]
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Insights
Chronic paroxysmal hemicrania (CPH) is a rare headache syndrome characterized by daily, strictly unilateral attacks. Prompt response to indomethacin is key for diagnosis, as detailed in these case reports.
Area of Science:
- Neurology
- Headache Medicine
Background:
- Chronic paroxysmal hemicrania (CPH) is a rare headache syndrome.
- Approximately 60 cases have been documented globally since its initial description in 1974.
Observation:
- CPH presents with daily headache attacks that are strictly unilateral.
- Attacks occur frequently, ranging from 5 to 30 episodes within a 24-hour period.
- Individual attacks are typically brief, lasting from 2 to 30 minutes.
Findings:
- The hallmark diagnostic criterion for CPH is a rapid and positive response to indomethacin treatment.
- This report details the clinical presentation, therapeutic interventions, pathogenetic considerations, and differential diagnosis of CPH.
- These represent the first reported cases of CPH in West Germany.
Implications:
- Highlights the diagnostic significance of indomethacin responsiveness in CPH.
- Contributes to the understanding and management of rare headache disorders.
- Expands the geographical case reporting of CPH.
Abstract:
Chronic paroxysmal Hemicrania (CPH) is a headache syndrome first described in 1974. Since then about 60 cases have been reported in the world literature. CPH is characterised by headache attacks occurring daily and always strictly unilaterally. The frequency of the attacks varies from 5 to 30 per 24 hours, the single attack having an usual length of 2 to 30 minutes. The prompt response to indomethacin is the decisive diagnostic criterion of this headache syndrome. The clinical picture, the treatment, some aspects of the pathogenesis and the differential diagnosis of CPH are described by means of case reports. To our knowledge these are the first four cases reported in West Germany.
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