CL 259,971: a potent new polyether anticoccidial. 2. Floor-pen trials.

Area of Science:

• Poultry Science
• Veterinary Parasitology
• Animal Nutrition

Background:

• Coccidiosis is a significant parasitic disease in poultry.
• Effective anticoccidial drugs are crucial for maintaining flock health and productivity.
• Previous studies indicated potential anticoccidial activity of CL 259,971.

Purpose of the Study:

• To confirm and evaluate the anticoccidial efficacy of CL 259,971 in floor-pen trials.
• To determine the optimal dosage of CL 259,971 for poultry.
• To compare the performance of CL 259,971 with existing anticoccidial agents.

Main Methods:

• Three floor-pen trials were conducted to assess anticoccidial activity.
• Various dietary levels of CL 259,971 were tested.
• Performance metrics including weight gain and overall performance were monitored.
• Comparisons were made against arprinocid and monensin.

Main Results:

• CL 259,971 exhibited high anticoccidial activity in floor-pen settings.
• The optimal dietary dosage was determined to be 5 ppm.
• At 5 ppm, CL 259,971 showed no adverse effects on poultry weight or performance.
• Efficacy and performance were comparable to arprinocid and monensin.

Conclusions:

• CL 259,971 is a highly effective anticoccidial agent for poultry.
• A dosage of 5 ppm in the diet is recommended for optimal results.
• CL 259,971 offers a viable alternative to current anticoccidial drugs, maintaining performance and health.