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Leiomyomatosis in the pelvic lymph node and peritoneum
Acta Pathologica Japonica
|July 1, 1984
Summary
This study details rare cases of pelvic lymph node leiomyomatosis and disseminated peritoneal leiomyomatosis. Both conditions, despite secondary nodules, exhibited benign histology, suggesting a favorable prognosis.
Area of Science:
- Gynecologic Pathology
- Surgical Oncology
Background:
- Leiomyomatosis, a rare condition involving smooth muscle tumors, can manifest in various locations.
- Disseminated peritoneal leiomyomatosis and pelvic lymph node leiomyomatosis are uncommon clinical entities.
Observation:
- The study presents two cases: a 50-year-old Japanese woman with pelvic lymph node leiomyomatosis and a 41-year-old woman with disseminated peritoneal leiomyomatosis.
- Both patients presented with leiomyomas, including daughter nodules, which histologically demonstrated benign features.
Findings:
- Histopathological examination confirmed benign features in all leiomyomas, irrespective of the presence of daughter nodules.
- The morphogenesis of discontinuous leiomyomas was explored, with a focus on their relationship to pelvic endometriosis.
Implications:
- Leiomyomatosis, even with disseminated nodules, generally carries a favorable prognosis.
- Conservative surgical extirpation is recommended as the primary therapeutic approach, avoiding overly aggressive treatments.