Jove
Visualize
Contact Us

Related Experiment Videos

Bacteremic pneumococcal pneumonia in the elderly.

T F Murphy, B C Fine

    The American Journal of the Medical Sciences
    |October 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Novel approach for tracking interdisciplinary research productivity using institutional databases.

    Journal of clinical and translational science·2022
    Same author

    Discovery and Contribution of Nontypeable Haemophilus influenzae NTHI1441 to Human Respiratory Epithelial Cell Invasion.

    Infection and immunity·2019
    Same author

    Moraxella catarrhalis-specific Th1 cells in BAL fluids of chronic obstructive pulmonary disease patients.

    International journal of immunopathology and pharmacology·2010
    Same author

    Mucosal immunization of mice with recombinant OMP P2 induces antibodies that bind to surface epitopes of multiple strains of nontypeable Haemophilus influenzae.

    Mucosal immunology·2008
    Same author

    Natural materno-fetal transfer of antibodies to PspA and to PsaA.

    Clinical and experimental immunology·2004
    Same author

    Cancer cachexia is mediated in part by the induction of IL-6-like cytokines from the spleen.

    Cytokine·2002
    Same journal

    Providers' Perspectives on Hospital-Based Tobacco Treatment Efforts.

    The American journal of the medical sciences·2026
    Same journal

    In Memoriam: Maurice A. Mufson, MD, MACP.

    The American journal of the medical sciences·2026
    Same journal

    Outcomes of acute myeloid leukemia patients admitted to the intensive care unit within 100 days of allogeneic hematopoietic stem cell transplantation.

    The American journal of the medical sciences·2026
    Same journal

    Association Between Reverse Triiodothyronine and Cardiac Complications in Patients with Uncontrolled Graves' Disease.

    The American journal of the medical sciences·2026
    Same journal

    Chlorthalidone vs. hydrochlorothiazide in hypertension management: Lessons for guiding clinical practice.

    The American journal of the medical sciences·2026
    Same journal

    The impact of COVID-19 on alcohol-associated hepatitis and alcohol-associated cirrhosis.

    The American journal of the medical sciences·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Pneumococcal pneumonia in the elderly often presents subtly, with fever, confusion, and dehydration being common. Early recognition of these signs is crucial for timely treatment and reducing high mortality rates.

    Area of Science:

    • Medicine
    • Infectious Diseases
    • Geriatrics

    Background:

    • Pneumococcal pneumonia is a significant health concern in the elderly population.
    • Bacteremic pneumococcal pneumonia presents unique diagnostic challenges in older adults.

    Purpose of the Study:

    • To review the clinical and laboratory features of bacteremic pneumococcal pneumonia in elderly patients.
    • To identify common presentations and associated pathogens.
    • To assess the prevalence of vaccine-serotype pneumococcal infections.

    Main Methods:

    • Retrospective review of 29 elderly patients with bacteremic pneumococcal pneumonia over five years.
    • Analysis of clinical manifestations, laboratory findings, and sputum/blood cultures.
    • Serotyping of blood isolates to determine capsular types.

    Related Experiment Videos

    Main Results:

    • 50% of patients lacked typical pneumonia symptoms; common presentations included fever, altered mental status, and dehydration.
    • 60% had other pulmonary pathogens identified alongside pneumococcus.
    • Reversible liver function abnormalities were frequent.
    • 69% of infections were caused by vaccine-included serotypes.

    Conclusions:

    • Subtle presentations of pneumococcal pneumonia in the elderly necessitate heightened clinical awareness for earlier diagnosis and treatment.
    • The presence of other pathogens and reversible liver abnormalities are notable findings.
    • Continued surveillance of pneumococcal serotypes is vital to monitor vaccine impact and emergence of non-vaccine types.
    • The high mortality rate underscores the need for effective pneumococcal vaccines in this demographic.