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[Treatment of gastroenteritis dehydration with a gluco-electrolytic solution given orally in a hospital milieu]
Insights
Oral rehydration therapy with a specific glucoelectrolytic solution effectively treats acute diarrhea and dehydration in young children. This treatment promotes rapid clinical recovery and restores fluid balance, making it a priority intervention.
Area of Science:
- Pediatrics
- Gastroenterology
- Clinical Nutrition
Context:
- Acute diarrhea and dehydration are common in infants and young children.
- Hospitalized pediatric patients require effective and safe rehydration strategies.
- Electrolyte and fluid imbalances necessitate prompt therapeutic intervention.
Purpose:
- To evaluate the therapeutic efficacy of an oral glucoelectrolytic solution in hospitalized children aged 1-36 months with acute diarrhea and/or dehydration.
- To assess the impact of the solution on clinical recovery and hydroelectrolytic status.
- To determine if the solution promotes physiological recovery, indicated by fluid intake patterns.
Summary:
- A study involving 132 hospitalized children (1-36 months) with acute diarrhea/dehydration utilized an oral glucoelectrolytic solution (Na 50 mEq/l, K 30 mEq/l, CO3H 24 mMol/l, glucose 111 mMol/l, saccharose 55 mMol/l, osmolarity 300 mOsm/l).
- The solution led to simultaneous clinical recovery and normalization of hydroelectrolytic disturbances (p < 0.05).
- Observed differences in fluid intake between dehydrated and hydrated children, and over time, indicated physiological recovery (p < 0.05).
Impact:
- The study supports the prioritization of this oral glucoelectrolytic solution over other treatments, even for hospitalized pediatric patients.
- Effective management of diarrhea and dehydration in children can reduce hospital stays and improve outcomes.
- This research contributes to evidence-based guidelines for pediatric fluid and electrolyte management.
Abstract:
We analyze the therapeutical value of an oral glucoelectrolytic solution when treating 132 hospitalized patients ranging from 1 to 36 months of age, with acute diarrhea and/or dehydration. These children were offered ad libitum a solution containing: Na 50 mEq/l, K 30 mEq/l, CO3H 24 mMol/l, glucose 111 mMol/l, and saccharose 55 mMol/l, with an osmolarity of 300 mOsm/1. We observed a simultaneous clinical recovery and normalization of the hydroelectrolytic disturbances (p less than 0.05). Furthermore the differences in the ingested quantities by dehydrated and well hydrated children (p less than 0.05), or as expressed in ml/kg/hour during the first six hours compared with the following hours in the whole group (p less than 0.05), demonstrate a physiological recovers of the patient. We conclude that the use of these solutions should have priority over other treatment even in hospitalized patients.