[Electrophysiological characteristics, nature and localization of the hepatic osmoreceptors]

Functional characteristics of 45 osmosensitive units of the liver were analysed under conditions of intraportal administration of different osmotic stimuli. The most effective stimulus was the distilled water, the other substances, according to intensity of the response, were arranged in the following order: NaCl greater than glucose greater than or equal to mannitol. The latency of response varied from 1.5 to 10 sec, and the rate and duration of impulsation were dependent on tonicities of solutions. True osmoreceptors are supposed to exist in the liver tissue.