Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bleeding disorders and non-accidental injury.

A E O'Hare, O B Eden

    Archives of Disease in Childhood
    |September 1, 1984
    PubMed
    Summary

    Bruising in children may indicate non-accidental injury or a bleeding disorder. Investigations revealed 16% of children had abnormal results, highlighting the overlap between these conditions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Anaemia in a Blood-Donating Physician.

    Journal of the Royal College of Physicians of London·2019
    Same author

    Central venous catheter tip position and malfunction in a paediatric oncology unit.

    Pediatric surgery international·2013
    Same author

    The development of evidence-based guidelines on mouth care for children, teenagers and young adults treated for cancer.

    European journal of cancer (Oxford, England : 1990)·2010
    Same author

    Absence of urinary opioid peptides in children with autism.

    Archives of disease in childhood·2008
    Same author

    Interventions for preventing oral mucositis for patients with cancer receiving treatment.

    The Cochrane database of systematic reviews·2007
    Same author

    Interventions for treating oral candidiasis for patients with cancer receiving treatment.

    The Cochrane database of systematic reviews·2007

    Area of Science:

    • Pediatrics
    • Hematology
    • Forensic Medicine

    Background:

    • Non-accidental injury (NAI) in children often presents with bruising.
    • Distinguishing NAI from underlying bleeding disorders is crucial for accurate diagnosis and management.

    Observation:

    • Fifty children with suspected NAI underwent comprehensive hemostasis and coagulation testing.
    • Initial investigations included complete blood count, platelet analysis, prothrombin time, partial thromboplastin time, fibrinogen, and bleeding time.

    Findings:

    • Abnormal results were observed in 16% of the children investigated.
    • One child presented with severe coagulopathy due to acquired inhibitors.
    • Other identified bleeding issues included von Willebrand's disease, platelet aggregation defects, and salicylate-induced platelet dysfunction.

    Implications:

    • Bleeding disorders are not uncommon in cases of suspected NAI.
    • The presence of a bleeding disorder does not exclude NAI; the conditions can coexist.
    • Accurate diagnostic workup is essential to differentiate or identify concurrent conditions, impacting legal and clinical outcomes.

    Related Experiment Videos