Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Unanticipated postoperative ventricular tachyarrhythmias.

I L Kron, J P DiMarco, P K Harman

    The Annals of Thoracic Surgery
    |October 1, 1984
    PubMed
    Summary

    Cardiac surgery can trigger dangerous arrhythmias like ventricular tachycardia or fibrillation. Early suppression of ventricular ectopy with drugs like lidocaine may not prevent these life-threatening events post-operation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Receptor for advanced glycation end products (RAGE) on iNKT cells mediates lung ischemia-reperfusion injury.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2013
    Same author

    Surgical treatment of the failing heart.

    Minerva cardioangiologica·2005
    Same author

    Risk-stratified approach to hybrid transcatheter-surgical palliation of hypoplastic left heart syndrome.

    Pediatric cardiology·2005
    Same author

    A comparison of rate control and rhythm control in patients with atrial fibrillation.

    The New England journal of medicine·2002
    Same author

    Repair of an anomalous left coronary artery.

    Cardiovascular surgery (London, England)·2002
    Same author

    The role of left ventricular reconstruction for cardiogenic shock.

    Seminars in thoracic and cardiovascular surgery·2002

    Area of Science:

    • Cardiology
    • Cardiac Surgery
    • Electrophysiology

    Background:

    • New sustained ventricular tachycardia or fibrillation can occur post-cardiac operations.
    • These arrhythmias may lead to hemodynamic compromise and can be fatal.

    Purpose of the Study:

    • To investigate the incidence and characteristics of new sustained ventricular arrhythmias after cardiac operations.
    • To evaluate the effectiveness of antiarrhythmic drugs and electrophysiological studies in managing these arrhythmias.

    Main Methods:

    • Retrospective analysis of 1,251 patients undergoing cardiac operations over three years.
    • Review of patient data including arrhythmias, treatments, and outcomes.
    • Electrophysiological studies and programmed ventricular stimulation in survivors.

    Related Experiment Videos

    Main Results:

    • 1.4% of patients developed new sustained ventricular tachycardia or fibrillation.
    • Arrhythmias often occurred within 48 hours postoperatively.
    • Lidocaine did not prevent arrhythmias in patients receiving it for ectopy.
    • 5 patients died from initial episodes; 2 deaths were linked to antiarrhythmic drug toxicity.
    • Electrophysiological studies reproduced arrhythmias in all tested survivors.
    • 2 late sudden deaths occurred in patients not adequately treated or studied.

    Conclusions:

    • Cardiac surgery can unmask or induce potentially lethal arrhythmias.
    • Pharmacological suppression of ventricular ectopy is not always effective in preventing early postoperative arrhythmias.
    • Electrophysiological study can aid in guiding appropriate prophylactic therapy for these patients.