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Clonidine treatment in paroxysmal localized hyperhidrosis
Archives of Neurology
|November 1, 1984
Summary
Two rare cases of paroxysmal localized hyperhidrosis (PLH) were successfully treated with clonidine hydrochloride. This medication offers a potential alternative to traditional local or surgical interventions for managing this rare sweating disorder.
Area of Science:
- Neurology
- Dermatology
Background:
- Paroxysmal localized hyperhidrosis (PLH) is a rare disorder with typically unknown causes.
- The condition is characterized by sudden, localized episodes of excessive sweating.
Observation:
- Two patients with paroxysmal localized hyperhidrosis were treated with clonidine hydrochloride.
- Treatment was based on the hypothesis that PLH originates in the central nervous system (CNS), potentially the hypothalamus.
Findings:
- Both patients exhibited a favorable response to clonidine hydrochloride treatment.
- Clonidine hydrochloride effectively managed the symptoms of paroxysmal localized hyperhidrosis in these cases.
Implications:
- Clonidine hydrochloride presents a viable pharmacological alternative for managing PLH.
- This approach may reduce the need for invasive local or surgical treatments for paroxysmal localized hyperhidrosis.