Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Age-related glucose intolerance in hyperthyroid patients.

K Ikejiri, T Yamada, H Ogura

    Diabetes
    |May 1, 1978
    PubMed
    Summary

    Aging impairs glucose tolerance, especially in hyperthyroid patients due to reduced insulin response. This study investigates age-related metabolic changes and thyroid hormone levels.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Efficacy and safety of anticoagulant therapy in three specific populations with sepsis: a meta-analysis of randomized controlled trials.

    Journal of thrombosis and haemostasis : JTH·2015
    Same author

    Recombinant human soluble thrombomodulin in severe sepsis: a systematic review and meta-analysis.

    Journal of thrombosis and haemostasis : JTH·2015
    Same author

    Field performance and cytology of protoplast-derived rice (Oryza sativa): high yield and low degree of variation of four japonica cultivars.

    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
    Same author

    Communicating by electrolarynx with a blind tetraplegic spinal cord injury patient on mechanical ventilation in the ICU.

    Spinal cord·2013
    Same author

    Time-resolved optical mammography and its preliminary clinical results.

    Technology in cancer research & treatment·2011
    Same author

    Interleukin-1β causes long-term potentiation deficiency in a mouse model of septic encephalopathy.

    Neuroscience·2011

    Area of Science:

    • Endocrinology
    • Gerontology
    • Metabolic Research

    Background:

    • Age-related metabolic changes are common.
    • Thyroid hormones influence glucose metabolism.
    • Hyperthyroidism can affect metabolic processes.

    Purpose of the Study:

    • To investigate age-related glucose intolerance and insulin response.
    • To examine thyroid hormone (T4, T3) and cholesterol levels in aging.
    • To compare metabolic changes in normal aging versus hyperthyroid aging.

    Main Methods:

    • Assessed oral glucose tolerance and serum insulin levels.
    • Measured serum thyroxine (T4) and triiodothyronine (T3) concentrations.
    • Analyzed serum total cholesterol in normal and hyperthyroid subjects across age groups.

    Main Results:

    • Serum T3 decreased with age in normal subjects and hyperthyroid patients.
    • Serum total cholesterol increased with age in normal subjects.
    • Age-related glucose intolerance was more pronounced in hyperthyroid patients due to diminished insulin response.

    Conclusions:

    • Age-related glucose intolerance is exacerbated by hyperthyroidism.
    • Reduced insulin secretion contributes to impaired glucose tolerance in aging hyperthyroid individuals.
    • Thyroid status significantly modulates the impact of aging on glucose metabolism.

    Related Experiment Videos