[Relation of K+-dependent cellular swelling to the state of cellular membranes]

It has been shown that after heating of ACE cells for 15 min at temperature 46 degrees C inhibition of K+-dependent swelling and a sharp decrease of cell resistance and capacity are observed. Changes of the parameters studied were of a threshold pattern, the threshold temperature proved to be uniform and equaled 46 degrees C. It is believed that the temperature relationships obtained point to an important role of barrier functions of cellular membranes in K+-dependent cell swelling.