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Related Experiment Videos

Methods of assessing the synovial fluid cell count.

D O Haskard, P A Revell

    Clinical Rheumatology
    |September 1, 1984
    PubMed
    Summary

    A new automated cell counter offers a fast, reliable method for synovial fluid cell counts, potentially replacing the traditional haemocytometer. A rapid testing strip showed high sensitivity but limited clinical value for synovial fluid analysis.

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    Area of Science:

    • Clinical chemistry
    • Haematology
    • Biomedical engineering

    Background:

    • Synovial fluid analysis is crucial for diagnosing joint diseases.
    • The haemocytometer is the conventional method for cell counting but is time-consuming.
    • Newer, faster methods are needed for efficient clinical assessment.

    Purpose of the Study:

    • To compare a rapid testing strip and an automated cell counter against the haemocytometer for synovial fluid cell counts.
    • To evaluate the clinical utility and reliability of these alternative methods.

    Main Methods:

    • Comparison of a rapid side-room testing strip, an automated cell counter, and the conventional haemocytometer.
    • Assessment of synovial fluid cell counts using all three methods.

    Main Results:

    • The testing strip was sensitive to granulocyte esterases but offered minimal advantage over visual inspection.
    • The automated cell counter provided fast and reliable cell counts.
    • The automated counter demonstrated potential as a haemocytometer replacement.

    Conclusions:

    • The automated cell counter is a viable and efficient alternative to the haemocytometer for synovial fluid cell counting.
    • The rapid testing strip has limited clinical utility for this application despite its sensitivity.

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