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Related Experiment Videos

Angiography in colonic carcinoma.

S Karlsson, K Jonsson, J E Rosengren

    Diseases of the Colon and Rectum
    |October 1, 1984
    PubMed
    Summary

    Mesenteric angiography in colon cancer patients revealed arterial encasement, indicating unresectability in most cases. Angiography aids in detecting recurrent disease missed by barium enemas.

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    Area of Science:

    • Gastroenterology
    • Oncology
    • Radiology

    Background:

    • Adenocarcinoma of the colon and rectum poses significant diagnostic and treatment challenges.
    • Accurate staging is crucial for determining surgical resectability and patient prognosis.

    Purpose of the Study:

    • To evaluate the utility of mesenteric angiography in assessing the resectability of colorectal adenocarcinoma.
    • To investigate the role of angiography in diagnosing recurrent colorectal cancer.

    Main Methods:

    • Mesenteric angiography was performed on 17 patients diagnosed with adenocarcinoma of the colon and rectum.
    • Tumor resectability was assessed based on intraoperative findings.
    • Intra-arterial chemotherapy with mitomycin C was administered to four patients.

    Main Results:

    • Encasement of the marginal artery was observed in 13 patients, with 10 deemed surgically unresectable.
    • Mesenteric arterial branch encasement was more frequent in unresectable (7/11) compared to resectable (2/5) tumors.
    • Angiography identified vascular infiltration in two patients with recurrent disease, where barium enemas were negative.
    • One patient showed a slight tumor size decrease following intra-arterial chemotherapy.

    Conclusions:

    • Mesenteric angiography is not definitive for establishing the resectability of colorectal carcinoma.
    • Angiography is valuable in detecting recurrent colorectal cancer, especially when conventional imaging is inconclusive.
    • Intra-arterial chemotherapy showed limited efficacy in this small patient cohort.

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