Tobacco use by narcoleptics and daytime sleep tendency

The nocturnal sleep and daytime sleep tendency were assessed in 10 narcoleptics who regularly smoked cigarettes and 10 narcoleptics who did not use tobacco. Standard sleep-wake polygraphic measures were recorded during the 24-h study. There were no statistical differences between groups in terms of nighttime sleep structure, although tobacco use resulted in a decreased sleep duration. Smokers tended to fall asleep more rapidly than non-smokers throughout daytime multiple sleep latency testing. The data failed to demonstrate a daytime arousal effect of tobacco for patients with narcolepsy.