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Related Experiment Videos

Amphetamine secretion in breast milk.

E Steiner, T Villén, M Hallberg

    European Journal of Clinical Pharmacology
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Amphetamine was found in breast milk at higher concentrations than in maternal plasma in a narcolepsy patient. Infant urine also contained small amounts of amphetamine, indicating potential infant exposure.

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    Area of Science:

    • Pharmacology
    • Neonatal Studies
    • Toxicology

    Background:

    • Narcolepsy treatment often involves stimulant medications like amphetamines.
    • Assessing medication transfer into breast milk is crucial for nursing mothers.

    Observation:

    • A nursing mother with narcolepsy received daily amphetamine treatment.
    • Amphetamine levels in breast milk were monitored post-delivery.

    Findings:

    • Amphetamine concentrations in breast milk were 3-7 times higher than maternal plasma levels.
    • Amphetamine was detected in the infant's urine, suggesting exposure.

    Implications:

    • Neonatal exposure to amphetamines via breast milk is possible.
    • Further research is needed on the safety of amphetamine use during lactation.