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Slipped epiphysis associated with hypothyroidism.

W Heyerman, D Weiner

    Journal of Pediatric Orthopedics
    |September 1, 1984
    PubMed
    Summary
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    Slipped capital femoral epiphysis (SCFE) may be more common in children with juvenile hypothyroidism. Thyroid hormone deficiency might weaken the femur

    Area of Science:

    • Pediatric Endocrinology
    • Orthopedics
    • Metabolic Bone Disease

    Background:

    • Juvenile hypothyroidism is a condition affecting thyroid hormone production in children.
    • Slipped capital femoral epiphysis (SCFE) is a hip condition occurring in adolescents.
    • The co-occurrence of these conditions is not well-established.

    Observation:

    • Seven cases of concurrent SCFE and juvenile hypothyroidism were identified.
    • This association appears more frequent than expected based on individual condition incidence.
    • Patients presented with SCFE during the course of diagnosed juvenile hypothyroidism.

    Findings:

    • Thyroid hormone deficiency is potentially linked to diminished strength in the epiphyseal growth plate of the femur.
    • A direct causal link requires further investigation, but a correlation is suggested.

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  • The pathophysiology may involve the impact of low thyroid hormone levels on bone development and stability.

    • Implications:

    • Clinicians should consider screening for SCFE in children diagnosed with juvenile hypothyroidism.
    • Further research is needed to elucidate the precise role of thyroid hormone in epiphyseal plate stability.
    • Understanding this association can improve diagnostic and therapeutic strategies for affected children.