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Lichenoid benign keratosis.

T G Berger, J H Graham, D K Goette

    Journal of the American Academy of Dermatology
    |October 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Lichenoid benign keratosis is a skin condition affecting fair-skinned individuals aged 35-65, often misdiagnosed clinically. Histopathology reveals characteristic features aiding in its diagnosis and differentiation from similar lesions.

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    Area of Science:

    • Dermatopathology
    • Histopathology
    • Immunofluorescence

    Background:

    • Lichenoid benign keratosis (LBK) presents common clinicopathologic features.
    • These include fair skin, age 35-65, female predominance, solitary lesions, and typical locations like the arm or presternal area.
    • Clinical recognition of LBK is frequently unsuccessful.

    Purpose of the Study:

    • To confirm previously observed clinicopathologic features of LBK.
    • To detail the histological diagnostic criteria for LBK.
    • To differentiate LBK from other similar skin conditions, such as lichen planus and solar keratosis.

    Main Methods:

    • Histopathologic examination of 108 LBK lesions from 104 patients.
    • Direct immunofluorescence studies on seven LBK tissue samples.

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  • Comparison of clinical and histopathological findings.

    • Main Results:

    • Histology confirms LBK diagnosis through lichenoid appearance, parakeratosis, plasma cells/eosinophils in infiltrate, and peripheral lentigo-like changes.
    • Direct immunofluorescence studies showed similarities to lichen planus.
    • Clinical suspicion of premalignant or malignant lesions aids in pathological diagnosis.

    Conclusions:

    • LBK shares features with lichen planus but has distinct histopathological characteristics.
    • Accurate diagnosis relies on combining clinical information with detailed histopathological analysis.
    • Distinguishing LBK from lichenoid solar keratosis is crucial for appropriate patient management.