Inhibitory effects of cerebellar cortical stimulation on sympathetic nerve activity in rabbits

In anaesthetized and paralyzed rabbits, renal sympathetic nerve activity was observed by integrating and averaging impulse discharges. The activity was readily depressed by stimulation with a train of a few pulses of lobules I, II, III, VIIa, and VIIIa. The effective sites which caused the marked depression on the sympathetic nerve activity were distributed in the ipsilateral vermal cortex, predominantly in the medial part. The latency of depression was around 200 msec. Stimulation of these lobules caused a reduction of the systemic blood pressure, but this effect required stimulation by repetitive pulses, for a period of up to 10 sec.