[Multifactorial malignancy analysis--modern knowledge in the practical diagnosis of head and neck tumors]

A pretherapeutical multi-step-check method of the diagnosis of malignancy is suggested as a basis of an individual therapy of tumours. It must comprise clinical tumour diagnosis (staging)--the tumour localizations, size and spreading of metastases--histopathological and histochemical grading of malignancy, and histological classification. Results of these diagnostic methods of 186 squamous-cell carcinomas of the head and neck were related to the survival rate. Histochemical LDH and G6PDH reactions and histopathological grading (G 1-group and G 3-group) are important criteria for prognosis.