Segmental serotoninergic innervation of spinal cord arterial circulation

A rich serotoninergic innervation of the anterior spinal artery has been evidenced by histofluorescence. The main contribution to this adventitial serotoninergic plexus appears to originate from a serotonin fiber network in the anterior horns: serotonin-containing fibers reach the dorsal termination of the sulcocommissural artery and run within its wall in a ventral direction, toward the anterior spinal artery. This segmental arrangement of blood vessel innervation could be the basis for a neurogenic control of local blood circulation.