Related Experiment Video

Updated: Aug 10, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Late prognosis of bronchial asthma in children

E Cserháti, G Mezei, J Kelemen

    Respiration; International Review of Thoracic Diseases
    |January 1, 1984
    PubMed

    Insights

    This study tracked 441 childhood asthma patients into adulthood, finding that 34% still had asthma at age 14, with symptoms recurring in some by age 26. Asthma attacks were less frequent in adulthood compared to childhood.

    Area of Science:

    • Pediatrics
    • Pulmonology
    • Epidemiology

    Background:

    • Childhood bronchial asthma is a common chronic respiratory condition.
    • Understanding the long-term natural course of asthma is crucial for effective management.
    • Previous studies have limited data on asthma persistence into adulthood.

    Purpose of the Study:

    • To investigate the natural progression of childhood bronchial asthma into young adulthood.
    • To determine the prevalence of asthma symptoms and recurrences in formerly asthmatic children.
    • To analyze the long-term outcomes and mortality associated with childhood asthma.

    Main Methods:

    • A longitudinal follow-up study of 441 patients diagnosed with childhood bronchial asthma.
    • Data collection involved questionnaires, personal interviews, and physical examinations.
    • The follow-up extended beyond the age of 14 years, with assessments at young adult ages.

    Main Results:

    • Asthma onset before age 2 occurred in 38% of patients.
    • At age 14, 34% of patients remained asthmatic.
    • By age 26, 43% experienced asthma complaints, though attack frequency decreased compared to childhood.
    • Five patients died, with 2 deaths attributed to asthma.

    Conclusions:

    • Childhood asthma often persists into or recurs in young adulthood.
    • The natural course of asthma shows a decrease in attack frequency but continued prevalence.
    • A diagram illustrating the natural course of childhood asthma was developed for practical application.

    More Related Videos

    Murine Model of Allergen Induced Asthma08:05

    Murine Model of Allergen Induced Asthma

    Published on: May 14, 2012

    Related Concept Videos

    Asthma: Pathogenesis and Management01:20

    Asthma: Pathogenesis and Management

    Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
    Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
    Asthma-III: Symptoms and Complications01:24

    Asthma-III: Symptoms and Complications

    Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
    Classification of Asthma
    Asthma-IV: Diagnostic and Management01:30

    Asthma-IV: Diagnostic and Management

    The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
    Clinical Assessment for Asthma:
    This is the first step in diagnosing and managing asthma. It includes:
    Asthma I: Introduction01:28

    Asthma I: Introduction

    Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
    Asthma III: Clinical Manifestations01:13

    Asthma III: Clinical Manifestations

    Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
    Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

    Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

    Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...