Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Baló's concentric sclerosis].

P Castaigne, R Escourolle, F Chain

    Revue Neurologique
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Correction: Gut barrier-microbiota imbalances in early life lead to higher sensitivity to inflammation in a murine model of C-section delivery.

    Microbiome·2023
    Same author

    Gut barrier-microbiota imbalances in early life lead to higher sensitivity to inflammation in a murine model of C-section delivery.

    Microbiome·2023
    Same author

    Over-production of exopolysaccharide by Lacticaseibacillus rhamnosus CNCM I-3690 strain cutbacks its beneficial effect on the host.

    Scientific reports·2023
    Same author

    Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime.

    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2020
    Same author

    STochastic Optical Reconstruction Microscopy (STORM) reveals the nanoscale organization of pathological aggregates in human brain.

    Neuropathology and applied neurobiology·2020
    Same author

    Cognitive deficit, and neuropathological correlates, in the oldest-old.

    Revue neurologique·2020
    Same journal

    Macrophage inclusions in patients undergoing antisense oligonucleotide therapy for ALS or SMA: A retrospective and transversal study.

    Revue neurologique·2026
    Same journal

    Geographic disparities in MRI features of ischemic stroke and small vessel disease: A comparative study between French Guiana and mainland France. Findings from the BECATOUR multicenter registry.

    Revue neurologique·2026
    Same journal

    Continuous subcutaneous perfusion of apomorphine in Parkinson's disease: Towards monotherapy?

    Revue neurologique·2026
    Same journal

    Neuro-Whipple presenting as autoimmune encephalitis.

    Revue neurologique·2026
    Same journal

    Multimodal assessment of minimally conscious state and cognitive motor dissociation in neurocritical care: A critical review.

    Revue neurologique·2026
    Same journal

    Development of a new episodic memory assessment tool (NEM): Preliminary data and clinical perspectives.

    Revue neurologique·2026
    See all related articles

    This case report details Baló

    Area of Science:

    • Neuropathology
    • Neuroimmunology
    • Neuroimaging

    Background:

    • Baló's concentric sclerosis is a rare, often fatal, demyelinating disease.
    • Its exact nosological position within inflammatory demyelinating diseases remains debated.
    • This report presents a unique case with comprehensive diagnostic investigations.

    Observation:

    • A 30-year-old male presented with acute neurological deficits including dizziness, gait disturbance, and hemihypoesthesia.
    • Cerebrospinal fluid analysis revealed elevated protein and cells.
    • CT scans showed characteristic hypodensities, and cerebral biopsy revealed concentric demyelination with astrogliosis and Rosenthal fibers.

    Findings:

    • Neuropathological examination confirmed extensive concentric demyelination across hemispheres, brainstem, and cerebellum.

    Related Experiment Videos

  • Light microscopy showed myelin breakdown products and astrocytic proliferation with Rosenthal fibers.
  • Electron microscopy highlighted oligodendrocyte and vascular integrity, with significant astrocytic alterations.

    • Implications:

    • This case is the first to combine CT imaging and electron microscopy in Baló's concentric sclerosis.
    • Findings contribute to understanding the ultrastructural pathology of Baló's disease.
    • Further research is needed to clarify its relationship with multiple sclerosis and other demyelinating disorders.