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In vitro fertilization and embryo transfer in Pretoria
Summary
This study presents the initial results of an in vitro fertilization program, achieving 2 ongoing third-trimester pregnancies from 67 induced cycles. Ongoing refinement of techniques is expected to improve future success rates in assisted reproductive technology.
Area of Science:
- Reproductive Medicine
- Gynecology
- In Vitro Fertilization
Background:
- The H. F. Verwoerd Hospital and University of Pretoria initiated an in vitro fertilization and embryo transfer program.
- The program aimed to provide assisted reproductive technology services to patients facing infertility.
Purpose of the Study:
- To detail the methodology and outcomes of the early phase of the IVF and ET program.
- To assess the initial success rates and identify areas for technical improvement.
Main Methods:
- Induced ovulation using clomiphene citrate and human chorionic gonadotrophin (hCG) or human postmenopausal gonadotrophin/hCG.
- Oocyte recovery via laparoscopy, with assessment of ovum viability and fertilization.
- Embryo transfer procedures were performed, with subsequent pregnancy monitoring.
Main Results:
- A 95% oocyte recovery rate was achieved in 42 patients undergoing 62 attempts.
- 179 ova were recovered, with 143 (80%) viable and 46% showing active cleavage.
- The program resulted in 5 pregnancies from 41 embryo transfers (12% per transfer), with 2 ongoing third-trimester pregnancies.
Conclusions:
- The initial IVF and ET program demonstrated feasibility and achieved successful pregnancies.
- Further consolidation and refinement of techniques are anticipated to enhance the center's success rates.
- The program represents a significant step in providing advanced reproductive services at the institution.