Acromegaly with multiple secreting pituitary adenomas

Area of Science:

• Endocrinology
• Neurosurgery
• Oncology

Background:

• Acromegaly is a disorder caused by excess growth hormone (GH) production, typically due to a pituitary adenoma.
• Pituitary adenomas are tumors of the pituitary gland, a small gland at the base of the brain.

Observation:

• This report details a rare case of acromegaly in a patient with two separate GH-secreting pituitary adenomas.
• Initial suspicion of multiplicity arose from computerized tomographic (CT) scan imaging.

Findings:

• Transsphenoidal surgery confirmed the presence of two distinct pituitary adenomas.
• Histopathological examination verified that both adenomas were secreting growth hormone.

Implications:

• The findings suggest that multiple pituitary adenomas, though rare, can occur and lead to conditions like acromegaly.
• This case underscores the importance of thorough diagnostic evaluation, including advanced imaging, for complex pituitary disorders.