[Preventive treatment of affective psychoses with finlepsin]

The prolonged (up to two years) use of finlepsin in manic-depressive and schizoaffective psychoses in 35 patients has shown this drug to possess a prophylactic effect comparable with the prophylactic action of lithium. In the course of treatment, the average cumulative duration of the morbid state considered in proportion to the observation period reduced from 87% to 37%. The dose of finlepsin reached as high as 1400 mg daily, with the average maintenance dose being 821 mg/day. Both critical and lytic variants of phasic reduction are traced.