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ECG abnormalities in polymyositis.

R Stern, J H Godbold, Q Chess

    Archives of Internal Medicine
    |November 1, 1984
    PubMed
    Summary
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    Electrocardiographic abnormalities are common in polymyositis patients. However, these heart issues showed no link to disease severity, suggesting close patient monitoring is crucial for inflammatory muscle disease.

    Area of Science:

    • Cardiology
    • Rheumatology
    • Neurology

    Background:

    • Polymyositis is an inflammatory myopathy.
    • Cardiac involvement in polymyositis is not fully understood.
    • Electrocardiographic (ECG) findings require further investigation.

    Purpose of the Study:

    • To investigate the prevalence and characteristics of electrocardiographic abnormalities in polymyositis patients.
    • To determine if ECG defects correlate with clinical disease activity or severity.
    • To assess the impact of treatment on ECG findings.

    Main Methods:

    • Retrospective analysis of 77 polymyositis patients.
    • Review of electrocardiograms (ECGs) for abnormalities.
    • Correlation of ECG findings with clinical data, disease duration, creatine kinase levels, age, and comorbidities.

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    Main Results:

    • Electrocardiographic abnormalities were present in 32.5% of patients.
    • Left anterior hemiblock (13.0%) and right bundle-branch block (9.1%) were most frequent.
    • No significant association found between ECG defects and clinical activity, disease duration, creatine kinase levels, age, or specific clinical conditions.
    • ECG improvement noted in two pediatric patients with corticosteroid therapy.
    • Three patients with heart block experienced sudden death.

    Conclusions:

    • Electrocardiographic abnormalities are frequent in polymyositis.
    • These cardiac defects do not appear to correlate with disease markers.
    • Sudden cardiac death occurred in a subset of patients with heart block.
    • Continuous monitoring of patients with inflammatory muscle diseases is essential, even during remission.