[Analysis of enkephalin conformation using circular dichroism and fluorescence spectroscopy]

Conformation of Leu- and Met-enkephalins and their 17 synthetic analogues was studied by CD and fluorescence spectroscopy both in dioxane and aqueous solutions. The results obtained indicate the beta-turn presence in dioxane solution for the most of the peptides under study. An appreciable percentage of the conformations of this type seems to exist in aqueous solutions as well.