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Related Experiment Videos

Secondary mania associated with diltiazem.

G K Palat, E A Hooker, A Movahed

    Clinical Cardiology
    |November 1, 1984
    PubMed
    Summary

    Diltiazem, a calcium-channel blocker, effectively treats angina. However, this case report details a rare instance of mania with psychotic features developing in a patient taking diltiazem.

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    Area of Science:

    • Cardiology
    • Pharmacology
    • Psychiatry

    Background:

    • Diltiazem is a widely used calcium-channel blocker for managing angina pectoris, especially the vasospastic form.
    • Recent introduction of diltiazem in the United States market.
    • Noncardiac adverse effects associated with diltiazem are generally infrequent.

    Observation:

    • A case study is presented involving a patient who developed mania with psychotic features.
    • The adverse psychiatric event occurred during the patient's treatment with diltiazem.

    Findings:

    • This report highlights a rare, noncardiac adverse effect of diltiazem.
    • The patient exhibited symptoms of mania and psychosis while on the medication.

    Implications:

    • Clinicians should be aware of potential psychiatric side effects of diltiazem, including mania.
    • Further investigation into the neuropsychiatric effects of calcium-channel blockers may be warranted.
    • This case underscores the importance of monitoring for unusual adverse events in patients receiving new medications.

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