Estrogen-producing Sertoli cell tumor of the ovary--a case report

Estrogen-secreting Sertoli cell tumor of the ovary is rare. The few cases reported were characterized by metrorrhagia suggesting the hyperestrogenic state. An additional case of Sertoli cell tumor is reported in which the clinical picture is of secondary amenorrhea followed by metrorrhagia. The endocrinological status was investigated by hormonal assays showing a high level of estradiol, which was consistent with endometrial biopsy. A review of the literature together with a discussion on the histogenesis and diagnosis of the tumor is presented.