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Related Experiment Videos

Disseminated protothecosis in a dog.

S D Gaunt, R K McGrath, H U Cox

    Journal of the American Veterinary Medical Association
    |October 15, 1984
    PubMed
    Summary

    A dog died from protothecosis, a rare infection caused by Prototheca zopfii. This alga caused widespread organ damage, including skeletal muscle, heart, and brain lesions.

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    Area of Science:

    • Veterinary Pathology
    • Microbiology
    • Infectious Diseases

    Background:

    • Prototheca species are ubiquitous algae that can cause opportunistic infections in various animal species.
    • Canine protothecosis is a rare but serious disease, often presenting with gastrointestinal or cutaneous signs.

    Observation:

    • A dog presented with forelimb lameness, bilateral retinal detachment, and hemorrhagic diarrhea.
    • Post-mortem examination revealed multifocal lesions throughout the skeletal musculature, myocardium, liver, thyroid glands, kidneys, eyes, and brain.
    • Microscopic examination of lesions showed numerous organisms with minimal inflammatory response.

    Findings:

    • Morphological and cultural characteristics of the causative organisms were consistent with Prototheca.
    • Immunohistochemical staining confirmed the presence of Prototheca zopfii in tissue sections.

    Implications:

    • This case highlights the potential for Prototheca zopfii to cause severe, disseminated disease in dogs.
    • Accurate diagnosis requires a combination of histopathology, culture, and serological techniques.
    • Understanding the pathogenesis of canine protothecosis is crucial for developing effective treatment strategies.

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