Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The auditory neurophonic: basic properties.

R L Snyder, C E Schreiner

    Hearing Research
    |September 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Auditory neurophonic signals, including the auditory nerve neurophonic (ANN) and frequency following response (FFR), are primarily neural in origin, distinct from cochlear microphonics (CM). These responses reflect spatial summation of auditory nerve activity.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A goal programming approach for balancing diet costs and feed water use under different environmental conditions.

    Journal of dairy science·2019
    Same author

    Functional congruity in local auditory cortical microcircuits.

    Neuroscience·2016
    Same author

    Strategies for optical control and simultaneous electrical readout of extended cortical circuits.

    Journal of neuroscience methods·2015
    Same author

    Phosphorus doped Zn(1-x)Mg(x)O nanowire arrays.

    Nano letters·2009
    Same author

    Two thalamic pathways to primary auditory cortex.

    Neuroscience·2008
    Same author

    Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex.

    Proceedings of the National Academy of Sciences of the United States of America·2007
    Same journal

    Electrophysiologically-based electrode selection has the potential to improve speech perception in cochlear-implant users.

    Hearing research·2026
    Same journal

    Multivariate prediction of conductive dysfunction in well and NICU newborns using wideband acoustic immittance with acoustic reflex tests.

    Hearing research·2026
    Same journal

    TGF-β signaling regulates flat epithelium formation in severely injured adult mouse utricle through epithelial-mesenchymal transition.

    Hearing research·2026
    Same journal

    Membrane scaffolding in auditory hair cells - a molecular tightrope walk enables lateral wall stiffness and flexibility.

    Hearing research·2026
    Same journal

    Speech-in-noise recognition during hearing protector use: Human performance and acoustic prediction.

    Hearing research·2026
    Same journal

    Estimation of hair cell loss from audiograms.

    Hearing research·2026
    See all related articles

    Area of Science:

    • Auditory Neuroscience
    • Neurophysiology
    • Acoustics

    Background:

    • Auditory neurophonics, including the auditory nerve neurophonic (ANN) and frequency following response (FFR), can be recorded from cats during low-frequency auditory stimulation.
    • These signals are distinct from the cochlear microphonic (CM) and share properties with single auditory nerve units.

    Purpose of the Study:

    • To investigate the fundamental properties of auditory neurophonics.
    • To differentiate the neural origins of ANN and FFR from the CM.
    • To relate neurophonic properties to phase-locked activity in the auditory nerve.

    Main Methods:

    • Differential recording of the ANN using platinum-iridium electrodes on the auditory nerve.
    • Recording of the FFR from the scalp using silver wire.

    Related Experiment Videos

  • Comparison with round window-recorded CM under identical acoustic stimulation conditions.

    • Main Results:

    • Neurophonic responses (ANN and FFR) were found to be distinct from CM across various measures (amplitude, spectral components, frequency, time, masking).
    • Micro-injections of kainic acid into the cochlear nucleus had minimal effect on neurophonics.
    • Tetrodotoxin injections into the cochlea significantly reduced neurophonic responses while largely sparing the CM.

    Conclusions:

    • Below 90 dB SPL, the ANN is predominantly neural, and the FFR is largely neural, both distinct from CM.
    • Auditory neurophonics represent a spatial summation of neural activity in the auditory nerve.
    • These responses likely arise from phase-locked activity of single auditory nerve units to low-frequency stimuli.