A study of spermatozoan defects in wild-type and T:t-bearing mice

A comparative light and electron microscopic study was done on cauda epididymal spermatozoa from +/tx, T/+, T/tx, C57BL/6J, BALB/c and randomly breeding Swiss Albino mice. The results show that all of the males contain abnormal spermatozoa and that all contain the same types of defective gametes. No unique defect was found which can be correlated with the increased transmission frequency of the tx-bearing allele.