Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone blood flow measurement.

P Tothill

    Journal of Biomedical Engineering
    |October 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Determining bone blood flow is crucial. Radioactive microspheres offer the most accurate method for animal studies, unlike tracer clearance techniques which are flow-dependent and less reliable.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Re: "DXA in vivo BMD methodology: an erroneous and misleading research and clinical gauge of bone mineral status, bone fragility, and bone remodelling" by H.H. Bolotin (Bone 2007; 41:138-154).

    Bone·2007
    Same author

    Precision and accuracy of measuring changes in bone mineral density by dual-energy X-ray absorptiometry.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2007
    Same author

    Dual-energy X-ray absorptiometry measurements of fat and lean masses in subjects with eating disorders.

    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity·2004
    Same author

    Bone mineral and soft tissue measurements by dual-energy X-ray absorptiometry during growth.

    Bone·2002
    Same author

    Comparisons between a pencil beam and two fan beam dual energy X-ray absorptiometers used for measuring total body bone and soft tissue.

    The British journal of radiology·2001
    Same author

    Comparisons between Hologic QDR 1000W, QDR 4500A, and Lunar Expert dual-energy X-ray absorptiometry scanners used for measuring total body bone and soft tissue.

    Annals of the New York Academy of Sciences·2000

    Area of Science:

    • Physiology
    • Biomedical Engineering
    • Radiology

    Background:

    • Accurate measurement of bone blood flow is essential for understanding skeletal physiology and disease.
    • Existing methods for assessing bone perfusion have limitations in precision and applicability.

    Purpose of the Study:

    • To compare different methods for determining blood flow in bone.
    • To identify the most reliable technique for quantifying bone perfusion.

    Main Methods:

    • Comparison of techniques including tracer clearance and radioactive microspheres.
    • Detailed description of the radioactive microsphere method for animal studies.

    Main Results:

    • Tracer clearance methods are inaccurate due to flow-dependent extraction variations.

    Related Experiment Videos

  • Radioactive microspheres represent the optimal available technique for animal bone blood flow measurement.

    • Conclusions:

    • Radioactive microsphere technique is the gold standard for animal bone blood flow studies.
    • Tracer clearance methods should be used with caution due to inherent inaccuracies.