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This study defines infantile autism, covering its onset, development, diagnosis, management, and treatment. Researchers hypothesize a generalized neurological deficit, not gross brain changes, underlies autism in children.
Area of Science:
- Neuroscience
- Developmental Pediatrics
- Child Psychology
Background:
- Infantile autism is a complex developmental disorder.
- Understanding its etiology is crucial for effective intervention.
Purpose of the Study:
- To define infantile autism, including its manifestation, clinical progression, and diagnostic criteria.
- To propose a hypothesis regarding the underlying neurological basis of autism.
Main Methods:
- Literature review and synthesis of existing knowledge on infantile autism.
- Clinical observation and case analysis (implied).
Main Results:
- A comprehensive definition of infantile autism is provided.
- The study outlines the typical time of manifestation and clinical development.
- Differential diagnosis, management, and treatment strategies are discussed.
Conclusions:
- The authors hypothesize that autism is not caused by gross brain structural abnormalities.
- A generalized deficit in neurologic function across cerebral neurons is proposed as the likely cause of autism.
Abstract:
The authors define infantile autism, giving its time of manifestation, clinical development, differential diagnosis, management, and treatment. They hypothesize that the cause of autism probably will not be found in some consistent gross alteration in brain size or gross structure but that autistic children have some generalized deficit of neurologic function that is common to most or all cerebral neurons.