Gm allotypes in Finnish myasthenia gravis patients

Gm phenotype G1m 1,2, and 3 frequencies were examined in 103 Finnish myasthenia gravis patients. There were no significant differences as compared with the expected frequency, either in the total material or when patients were subdivided according to sex, age of onset of disease, thymus pathology, or presence of HLA-B8. However, individuals with Gm(+1) had a significantly higher concentration of antibodies against acetylcholine receptor, possibly indicating a correlation with severity of disease.