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Antitubercular 2,8-bis(alkylaminomethyl)phenazines
Journal of Medicinal Chemistry
|April 1, 1978
Abstract:
The preparation and antitubercular properties of a series of 2,8-bis(alkylaminomethyl)phenazines are described. These compounds all inhibited the growth of Mycobacterium smegmatis ATCC 607 in vitro. 2,8-Bis(dibutylaminomethyl)phenazine (5c) was also active against a lethal Mycobacterium tuberculosis H37Rv infection in mice.