[Pathology of advanced maxillary cancer following combined radiotherapy and surgical therapy]

Case report of a 44 year old patient with an invasive partially keratinizing squamous cell carcinoma which broke into the middle base of the skull and penetrated into the brain. By combined radiotherapy and chemotherapy a surgical treatment of the originally extensive primary tumor became possible. Histologically no cancer tissue was found in the resected parts. 2 1/2 years later the patient died from pneumonia. The autopsy revealed a "restitutio ad integrum" of the skull and brain which according to several computertomographies were invaded by the tumor.