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Amyloidosis in experimental tegumentary leishmaniasis in mice

E G Barbosa-Santos, S C da Costa, A Alencar

The American Journal of Tropical Medicine and Hygiene

|November 1, 1984

Abstract:

Renal and hepatosplenic amyloidosis was found in chronic cutaneous leishmaniasis in mice infected with 10(6) purified amastigotes from lesions produced by the H21 strain of Leishmania mexicana amazonensis. After 1 year a progressive lesion leading to metastasis was observed in most animals.

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