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Susceptibilities of 45 clinical isolates of Proteus penneri
Antimicrobial Agents and Chemotherapy
|September 1, 1984
Abstract:
Patterns of susceptibility of 45 Proteus penneri clinical isolates to 14 antimicrobial agents were evaluated by a macrobroth dilution method. All strains were highly susceptible to ceftizoxime, ceftazidime, moxalactam, cefoxitin, gentamicin, tobramycin, netilmicin, and, with few exceptions, to amikacin, piperacillin, and cefoperazone. Most strains were susceptible to cefotaxime and ceftriaxone. All strains were resistant to cefazolin and cefsulodin.
Insights
This study evaluated Proteus penneri susceptibility to 14 antimicrobial agents. All clinical isolates showed high susceptibility to several key antibiotics, including ceftizoxime and gentamicin.
Area of Science:
- Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Background:
- Proteus penneri is a significant opportunistic pathogen.
- Understanding its antimicrobial susceptibility is crucial for effective treatment.
Purpose of the Study:
- To determine the antimicrobial susceptibility patterns of clinical isolates of Proteus penneri.
- To identify effective antibiotics against Proteus penneri.
Main Methods:
- Macrobroth dilution method was used.
- Susceptibility testing was performed on 45 clinical isolates of Proteus penneri.
- Fourteen different antimicrobial agents were evaluated.
Main Results:
- All 45 strains were highly susceptible to ceftizoxime, ceftazidime, moxalactam, cefoxitin, gentamicin, tobramycin, and netilmicin.
- Most strains were susceptible to cefotaxime and ceftriaxone.
- All strains exhibited resistance to cefazolin and cefsulodin.
Conclusions:
- Ceftizoxime, ceftazidime, moxalactam, cefoxitin, gentamicin, tobramycin, and netilmicin are highly effective against Proteus penneri.
- Cefazolin and cefsulodin are not recommended for treating Proteus penneri infections.